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Degeneration of the brain due to alcohol

MESH PheWeb

G6_ALCODEGEN

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G31.2
Cause of death: ICD-10 G31.2

2 out of 7 registries used, show all original rules.

610

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Check minimum number of events None

610

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Include endpoints None

610

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Remove individuals based on genotype QC

592

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G6_ALCODEGEN

Control definitions

Control exclude G6_NEURODEG

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G31
Name in latin Degeneratio systematis nervosi ex alcohol (aethylico)

Summary Statistics

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Key figures

All Female Male
Number of individuals 592 91 501
Unadjusted prevalence (%) 0.16 0.04 0.30
Mean age at first event (years) 59.71 55.22 60.53

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.14 9.98 [4.82, 20.68] 6.1e-10 216
15 years 0.03 4.12 [1.93, 8.80] 2.6e-4 86
5 years 0.01 8.03 [4.96, 13.00] 2.5e-17 68
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_ALCODEGEN – Degeneration of the brain due to alcohol
GWS hits:

Survival analyses between endpoints

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Plot

before Degeneration of the brain due to alcohol
after Degeneration of the brain due to alcohol

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Drugs most likely to be purchased after Degeneration of the brain due to alcohol

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Endpoint not on priority list, no data to show.