Circumscribed brain atrophy

DOID MESH PheWeb

G6_ATROPHCIRCUM

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G31.0

Hospital discharge: ICD-9 3311

Hospital discharge: ICD-8 34791

Cause of death: ICD-10 G31.0

Cause of death: ICD-9 3311

Cause of death: ICD-8 34791

2 out of 7 registries used, show all original rules.

485

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Check minimum number of events None

485

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Include endpoints None

485

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Remove individuals based on genotype QC

467

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G6_ATROPHCIRCUM

Control definitions

Control exclude G6_NEURODEG

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF6

Parent code in ICD-10 G31

Name in latin Atrophia cerebri circumscripta

NAME	G6_ATROPHCIRCUM
CONTROL_EXCLUDE	G6_NEURODEG
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	G310
HD_ICD_9	3311
HD_ICD_8	34791
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	G310
COD_ICD_9	3311
COD_ICD_8	34791
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Similar endpoints

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List of similar endpoints to Circumscribed brain atrophy based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Frontotemporal dementia

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	467	207	260
Unadjusted prevalence (%)	0.12	0.10	0.16
Mean age at first event (years)	63.69	63.32	63.98

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_ATROPHCIRCUM – Circumscribed brain atrophy
GWS hits: 1

Survival analyses between endpoints

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Plot

before Circumscribed brain atrophy
after Circumscribed brain atrophy

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Table

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Drugs most likely to be purchased after Circumscribed brain atrophy

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Endpoint not on priority list, no data to show.