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Renal tubulo-interstitial diseases

DOID MESH PheWeb

N14_RENALTUB

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 N10-N16, N17-N19
Cause of death: ICD-10 N10-N16, N17-N19

2 out of 7 registries used, show all original rules.

35450

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Check minimum number of events None

35450

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Include endpoints

39767

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Remove individuals based on genotype QC

38335

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N14_RENALTUB

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 38335 20295 18040
Unadjusted prevalence (%) 10.17 9.63 10.85
Mean age at first event (years) 57.63 49.79 66.45

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 5.11 [4.52, 5.77] <1e-100 8836
15 years 0.01 1.79 [1.61, 2.00] 5.9e-26 2067
5 years 0.01 5.30 [4.86, 5.78] <1e-100 2995
1 year 0.00 22.62 [20.52, 24.93] <1e-100 3377

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: N14_RENALTUB – Renal tubulo-interstitial diseases
GWS hits: 2

Survival analyses between endpoints

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Plot

before Renal tubulo-interstitial diseases
after Renal tubulo-interstitial diseases

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Renal tubulo-interstitial diseases

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Endpoint not on priority list, no data to show.