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Tubulo-interstitial nephritis, not specified as acute or chronic

DOID EFO MESH SNOMED PheWeb

N14_TUBULOINTNEPHRNAS

pyelonephritis: Inflammation of the KIDNEY involving the renal parenchyma (the NEPHRONS); KIDNEY PELVIS; and KIDNEY CALICES. It is characterized by ABDOMINAL PAIN; FEVER; NAUSEA; VOMITING; and occasionally DIARRHEA.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 N12
Hospital discharge: ICD-9 5909
Hospital discharge: ICD-8 5909
Cause of death: ICD-10 N12
Cause of death: ICD-9 5909
Cause of death: ICD-8 5909

2 out of 7 registries used, show all original rules.

2189

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Check minimum number of events None

2189

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Include endpoints None

2189

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Remove individuals based on genotype QC

2110

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N14_TUBULOINTNEPHRNAS

Control definitions

Control exclude N14_RENALTUB

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 N10-N16
Name in latin Nephritis tubulo-interstitialis sine specificatione utrum acuta an chronica

Summary Statistics

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Key figures

All Female Male
Number of individuals 2110 1285 825
Unadjusted prevalence (%) 0.56 0.61 0.50
Mean age at first event (years) 53.86 46.43 65.43

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.09 5.76 [4.18, 7.92] 5.5e-27 522
15 years 0.01 1.60 [1.16, 2.22] 4.5e-3 121
5 years 0.01 5.46 [4.10, 7.26] 2.0e-31 185
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: N14_TUBULOINTNEPHRNAS – Tubulo-interstitial nephritis, not specified as acute or chronic
GWS hits:

Survival analyses between endpoints

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Plot

before Tubulo-interstitial nephritis, not specified as acute or chronic
after Tubulo-interstitial nephritis, not specified as acute or chronic

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Tubulo-interstitial nephritis, not specified as acute or chronic

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Endpoint not on priority list, no data to show.