≡ Risteys
R9

Documentation Changelog GitHub Contact & Feedback

Hydronephrosis

DOID EFO MESH SNOMED PheWeb

N14_HYDRONEPHR

hydronephrosis: Collection of urine in the renal pelvis that results in dilatation of the renal pelvis and calyces. It is caused by obstruction of urine flow, nephrolithiasis, or vesicoureteral reflux. Signs and symptoms include flank pain, nausea, vomiting, fever, and dysuria.

Endpoint definition

↥
FinnGen phenotype data

392423 individuals

diagram downward connector

Apply sex-specific rule None

392423

diagram downward connector

Check conditions None

392423

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 N13.0, N13.1, N13.2, N13.3
Hospital discharge: ICD-9 591
Hospital discharge: ICD-8 591
Cause of death: ICD-10 N13.0, N13.1, N13.2, N13.3
Cause of death: ICD-9 591
Cause of death: ICD-8 591

2 out of 7 registries used, show all original rules.

3379

diagram downward connector

Check minimum number of events None

3379

diagram downward connector

Include endpoints None

3379

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

3252

diagram downward connector
N14_HYDRONEPHR

Control definitions

Control exclude N14_RENALTUB

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 3252 1540 1712
Unadjusted prevalence (%) 0.86 0.73 1.03
Mean age at first event (years) 58.20 52.55 63.28

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.10 7.07 [5.42, 9.22] 5.1e-47 746
15 years 0.01 1.48 [1.11, 1.98] 8.1e-3 137
5 years 0.01 5.37 [4.11, 7.01] 6.5e-35 233
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: N14_HYDRONEPHR – Hydronephrosis
GWS hits:

Survival analyses between endpoints

↥

Plot

before Hydronephrosis
after Hydronephrosis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hydronephrosis

↥

Endpoint not on priority list, no data to show.