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Myeloproliferative diseases (CML excluded)

DOID MESH PheWeb

MYELOPROF_NONCML

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions

not CML

392175

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

1939

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Remove individuals based on genotype QC

1887

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MYELOPROF_NONCML

Control definitions

Control conditions not CML

Extra metadata

First used in FinnGen datafreeze DF2, additional

No data for upset plot.

No data for upset table.

Summary Statistics

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Key figures

All Female Male
Number of individuals 1887 979 908
Unadjusted prevalence (%) 0.50 0.46 0.55
Mean age at first event (years) 61.75 60.72 62.86

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.76 [2.54, 5.59] 4.7e-11 349
15 years 0.02 2.44 [1.84, 3.24] 7.1e-10 174
5 years 0.00 3.40 [2.63, 4.39] 6.3e-21 95
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: MYELOPROF_NONCML – Myeloproliferative diseases (CML excluded)
GWS hits: 15

Survival analyses between endpoints

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Plot

before Myeloproliferative diseases (CML excluded)
after Myeloproliferative diseases (CML excluded)

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Myeloproliferative diseases (CML excluded)

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Endpoint not on priority list, no data to show.