Other diseases of intestines

K11_INTESTOTH

intestinal volvulus: A twisting in the intestine (INTESTINES) that can cause INTESTINAL OBSTRUCTION.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K55-K63
Cause of death: ICD-10 K55-K63

2 out of 7 registries used, show all original rules.

67515

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Check minimum number of events None

67515

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Remove individuals based on genotype QC

75346

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K11_INTESTOTH

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 75346 42041 33305
Unadjusted prevalence (%) 19.98 19.94 20.03
Mean age at first event (years) 54.92 53.27 57.01

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.94 [1.76, 2.13] 3.1e-43 10292
15 years 0.01 1.18 [1.08, 1.28] 1.3e-4 3945
5 years 0.00 2.39 [2.22, 2.57] <1e-100 2680
1 year 0.00 8.76 [7.95, 9.65] <1e-100 1988

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: K11_INTESTOTH – Other diseases of intestines
GWS hits: 11

Survival analyses between endpoints

Plot

before Other diseases of intestines
after Other diseases of intestines

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Drugs most likely to be purchased after Other diseases of intestines

Endpoint not on priority list, no data to show.