Paralytic ileus and intestinal obstruction

K11_ILEUS

intestinal pseudo-obstruction: A type of ILEUS, a functional not mechanical obstruction of the INTESTINES. This syndrome is caused by a large number of disorders involving the smooth muscles (MUSCLE, SMOOTH) or the NERVOUS SYSTEM.

Endpoint definition

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FinnGen phenotype data

392423 individuals

Apply sex-specific rule None

392423

Check conditions None

392423

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K56

Cause of death: ICD-10 K56

2 out of 7 registries used, show all original rules.

7883

Check minimum number of events None

7883

Include endpoints

K11_PARALIL

K11_INTUSS

K11_VOLVU

K11_IMPACT

K11_ADHE

K11_OTHILEUS

8937

Remove individuals based on genotype QC

8660

K11_ILEUS

Control definitions

Control exclude K11_INTESTOTH

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 K55-K63

Name in latin Ileus paralyticus sive obstructio intestini sine hernia

NAME	K11_ILEUS
CONTROL_EXCLUDE	K11_INTESTOTH
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	K11_PARALIL\|K11_INTUSS\|K11_VOLVU\|K11_IMPACT\|K11_ADHE\|K11_OTHILEUS
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	K56
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	K56
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Or the full data table

Similar endpoints

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List of similar endpoints to Paralytic ileus and intestinal obstruction based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	8660	4221	4439
Unadjusted prevalence (%)	2.30	2.00	2.67
Mean age at first event (years)	59.83	56.81	62.69

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.06	4.12 [3.28, 5.19]	1.0e-33	2059
15 years	0.01	1.39 [1.12, 1.72]	3.0e-3	521
5 years	0.00	3.86 [3.24, 4.60]	5.8e-52	538
1 year	0.01	26.95 [23.14, 31.38]	<1e-100	834

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_ILEUS – Paralytic ileus and intestinal obstruction
GWS hits:

Survival analyses between endpoints

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Plot

before Paralytic ileus and intestinal obstruction
after Paralytic ileus and intestinal obstruction

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Table

Loading survival analyses table

Drugs most likely to be purchased after Paralytic ileus and intestinal obstruction

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Endpoint not on priority list, no data to show.

≡ Risteys

R9

R8

R7

R6

R5

R4

R3