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Irritable bowel syndrome

DOID EFO MESH SNOMED PheWeb

K11_IBS

irritable bowel syndrome: Gastrointestinal symptoms characterized by chronic abdominal pain and altered bowel habits in the absence of any organic cause.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K58
Hospital discharge: ICD-9 5641
Hospital discharge: ICD-8 56419
Cause of death: ICD-10 K58
Cause of death: ICD-9 5641
Cause of death: ICD-8 56419

2 out of 7 registries used, show all original rules.

9648

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Check minimum number of events None

9648

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Include endpoints None

9648

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Remove individuals based on genotype QC

9323

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K11_IBS

Control definitions

Control exclude K11_INTESTOTH

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 K55-K63
Name in latin Syndroma intestini irritabilis

Summary Statistics

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Key figures

All Female Male
Number of individuals 9323 6884 2439
Unadjusted prevalence (%) 2.47 3.27 1.47
Mean age at first event (years) 48.95 48.20 51.09

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.65 [1.31, 2.06] 1.6e-5 514
15 years 0.01 1.05 [0.83, 1.34] 6.7e-1 241
5 years 0.00 1.74 [1.35, 2.23] 1.3e-5 116
1 year 0.00 3.36 [2.36, 4.77] 1.5e-11 41

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_IBS – Irritable bowel syndrome
GWS hits:

Survival analyses between endpoints

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Plot

before Irritable bowel syndrome
after Irritable bowel syndrome

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Irritable bowel syndrome

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Endpoint not on priority list, no data to show.