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Haemmorrhoids and perianal venous thrombosis

DOID EFO MESH SNOMED PheWeb

K11_HAEMORR

hemorrhoid: Dilated veins in the anal canal.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K64
Hospital discharge: ICD-9 455
Hospital discharge: ICD-8 455
Cause of death: ICD-10 K64
Cause of death: ICD-9 455
Cause of death: ICD-8 455

2 out of 7 registries used, show all original rules.

8847

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Check minimum number of events None

8847

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Include endpoints None

8847

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Remove individuals based on genotype QC

8583

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K11_HAEMORR

Control definitions

Control exclude K11_INTESTOTH

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 8583 4278 4305
Unadjusted prevalence (%) 2.28 2.03 2.59
Mean age at first event (years) 46.85 46.38 47.31

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.93 [0.78, 1.11] 4.5e-1 1412
15 years 0.00 0.73 [0.63, 0.84] 2.5e-5 615
5 years 0.00 0.72 [0.60, 0.86] 4.2e-4 150
1 year 0.00 0.92 [0.65, 1.30] 6.3e-1 36

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_HAEMORR – Haemmorrhoids and perianal venous thrombosis
GWS hits: 8

Survival analyses between endpoints

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Plot

before Haemmorrhoids and perianal venous thrombosis
after Haemmorrhoids and perianal venous thrombosis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Haemmorrhoids and perianal venous thrombosis

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Endpoint not on priority list, no data to show.