Thoracic aortic aneurysm

I9_THAORTANEUR

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I71.01, I71.1, I71.2, Q25.43

Cause of death: ICD-10 I71.01, I71.1, I71.2, Q25.43

2 out of 7 registries used, show all original rules.

3616

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Check minimum number of events None

3616

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Include endpoints None

3616

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Remove individuals based on genotype QC

3510

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I9_THAORTANEUR

Control definitions

Control exclude I9_DOAAC

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF9

NAME	I9_THAORTANEUR
CONTROL_EXCLUDE	I9_DOAAC
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	I7101\|I71[12]\|Q2543
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	I7101\|I71[12]\|Q2543
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Show upset plot detailing case counts by codes

Or the full data table

Similar endpoints

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List of similar endpoints to Thoracic aortic aneurysm based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	3510	748	2762
Unadjusted prevalence (%)	0.93	0.35	1.66
Mean age at first event (years)	66.44	66.06	66.54

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	3.00 [2.05, 4.39]	1.7e-8	414
15 years	0.01	1.08 [0.73, 1.58]	7.1e-1	138
5 years	0.00	2.09 [1.47, 2.97]	3.5e-5	126
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_THAORTANEUR – Thoracic aortic aneurysm
GWS hits: 12

Survival analyses between endpoints

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Plot

before Thoracic aortic aneurysm
after Thoracic aortic aneurysm

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Thoracic aortic aneurysm

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Endpoint not on priority list, no data to show.