Aortic aneurysm

I9_AORTANEUR

aortic aneurysm: A ruptured aneurysm located in the wall of the proximal portion of the descending aorta proceeding from the arch of the aorta.

Endpoint definition

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FinnGen phenotype data

392423 individuals

Apply sex-specific rule None

392423

Check conditions None

392423

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I71.1, I71.2, I71.3, I71.4, I71.5, I71.6, I71.8, I71.9

Hospital discharge: ICD-9 441[1-9]|0930A

Hospital discharge: ICD-8 0930|441

Cause of death: ICD-10 I71.1, I71.2, I71.3, I71.4, I71.5, I71.6, I71.8, I71.9

Cause of death: ICD-9 441[1-9]|0930A

Cause of death: ICD-8 0930|441

2 out of 7 registries used, show all original rules.

7499

Check minimum number of events None

7499

Include endpoints

I9_ABAORTANEUR

I9_THAORTANEUR

7600

Remove individuals based on genotype QC

7395

I9_AORTANEUR

Control definitions

Control exclude I9_DOAAC

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

NAME	I9_AORTANEUR
CONTROL_EXCLUDE	I9_DOAAC
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	I9_ABAORTANEUR\|I9_THAORTANEUR
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	I71[1-9]
HD_ICD_9	441[1-9]\|0930A
HD_ICD_8	0930\|441
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	I71[1-9]
COD_ICD_9	441[1-9]\|0930A
COD_ICD_8	0930\|441
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Show upset plot detailing case counts by codes

Or the full data table

Similar endpoints

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List of similar endpoints to Aortic aneurysm based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	7395	1123	6272
Unadjusted prevalence (%)	1.96	0.53	3.77
Mean age at first event (years)	68.26	66.36	68.60

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.08	5.14 [4.40, 6.00]	1.3e-95	2199
15 years	0.01	2.14 [1.86, 2.46]	3.3e-26	782
5 years	0.00	3.97 [3.51, 4.50]	<1e-100	652
1 year	0.00	18.31 [16.06, 20.87]	<1e-100	663

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_AORTANEUR – Aortic aneurysm
GWS hits: 18

Survival analyses between endpoints

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Plot

before Aortic aneurysm
after Aortic aneurysm

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Aortic aneurysm

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Endpoint not on priority list, no data to show.

≡ Risteys

R9

R8

R7

R6

R5

R4

R3