Diseases of arteries, arterioles and capillaries (FINNGEN)

FG_DOAAC

vascular disease: A non-neoplastic or neoplastic disorder affecting the arteries, veins, or lymphatic vessels. Examples include vasculitis, thrombophlebitis, arteriosclerosis, lymphedema, hemangioma, and angiosarcoma.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Remove individuals based on genotype QC

22224

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FG_DOAAC

Control definitions

Control exclude FG_CVD

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Diseases of arteries, arterioles and capillaries (FINNGEN) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

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Summary Statistics

Key figures

All Female Male
Number of individuals 22224 6023 16201
Unadjusted prevalence (%) 5.89 2.86 9.74
Mean age at first event (years) 67.49 67.26 67.58

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 4.92 [4.39, 5.52] <1e-100 7818
15 years 0.02 2.50 [2.28, 2.75] 7.0e-82 3027
5 years 0.01 4.36 [4.02, 4.73] <1e-100 2375
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: FG_DOAAC – Diseases of arteries, arterioles and capillaries (FINNGEN)
GWS hits: 29

Survival analyses between endpoints

Plot

before Diseases of arteries, arterioles and capillaries (FINNGEN)
after Diseases of arteries, arterioles and capillaries (FINNGEN)

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Drugs most likely to be purchased after Diseases of arteries, arterioles and capillaries (FINNGEN)

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