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Hypertension, essential

DOID MESH PheWeb

I9_HYPTENSESS

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I10
Hospital discharge: ICD-9 4039A|4019X
Hospital discharge: ICD-8 401|402|403|404
Cause of death: ICD-10 I10
Cause of death: ICD-9 4039A|4019X
Cause of death: ICD-8 401|402|403|404

2 out of 7 registries used, show all original rules.

95280

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Check minimum number of events None

95280

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Include endpoints None

95280

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Remove individuals based on genotype QC

92462

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I9_HYPTENSESS

Control definitions

Control exclude I9_HYPERTENSION

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I10-I15
Name in latin Hypertensio essentialis (primaria)

Summary Statistics

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Key figures

All Female Male
Number of individuals 92462 44535 47927
Unadjusted prevalence (%) 24.52 21.13 28.82
Mean age at first event (years) 63.24 62.80 63.65

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 3.02 [2.78, 3.28] <1e-100 16313
15 years 0.01 1.73 [1.59, 1.87] 2.5e-40 6633
5 years 0.00 3.23 [3.02, 3.45] <1e-100 4860
1 year 0.00 10.63 [9.70, 11.66] <1e-100 3254

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_HYPTENSESS – Hypertension, essential
GWS hits: 191

Survival analyses between endpoints

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Plot

before Hypertension, essential
after Hypertension, essential

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hypertension, essential

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