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Heart failure, not strict

I9_HEARTFAIL_NS

systolic heart failure: Heart failure caused by abnormal myocardial contraction during systole leading to defective cardiac emptying.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I11.0, I13.0, I13.2, I50
Hospital discharge: ICD-9 4029B|428
Hospital discharge: ICD-8 42700|42710|428|7824
Cause of death: ICD-10 I11.0, I13.0, I13.2, I50
Cause of death: ICD-9 4029B|428
Cause of death: ICD-8 42700|42710|428|7824
KELA reimbursements: KELA codes 201
Medicine purchases: ATC C03CA01|C03EB01

4 out of 7 registries used, show all original rules.

50808

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Check minimum number of events

Min. number of events 3

50808

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Include endpoints None

50808

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Remove individuals based on genotype QC

49172

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I9_HEARTFAIL_NS

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF6

Summary Statistics

Key figures

All Female Male
Number of individuals 49172 21071 28101
Unadjusted prevalence (%) 13.04 10.00 16.90
Mean age at first event (years) 66.68 65.07 67.88

Mortality

Not a core endpoint, no data to show.

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Not a core endpoint, no data to show.

Correlations

Index endpoint: I9_HEARTFAIL_NS – Heart failure, not strict
GWS hits:

Survival analyses between endpoints

Not a core endpoint, no data to show.

Drugs most likely to be purchased after Heart failure, not strict

Endpoint not on priority list, no data to show.