Heart failure and antihypertensive medication

I9_HEARTFAIL_AND_ANTIHYPERT

No definition available.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions

RX_ANTIHYP

205772

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

26675

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Remove individuals based on genotype QC

25827

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I9_HEARTFAIL_AND_ANTIHYPERT

Control definitions

Control conditions not RX_ANTIHYP

Extra metadata

First used in FinnGen datafreeze DF5

Summary Statistics

Key figures

All Female Male
Number of individuals 25827 9526 16301
Unadjusted prevalence (%) 6.85 4.52 9.80
Mean age at first event (years) 69.07 69.25 68.97

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 4.41 [3.87, 5.01] <1e-100 10852
15 years 0.02 2.40 [2.17, 2.65] 1.1e-65 4586
5 years 0.01 3.86 [3.58, 4.17] <1e-100 3434
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_HEARTFAIL_AND_ANTIHYPERT – Heart failure and antihypertensive medication
GWS hits: 38

Survival analyses between endpoints

Plot

before Heart failure and antihypertensive medication
after Heart failure and antihypertensive medication

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Drugs most likely to be purchased after Heart failure and antihypertensive medication

Endpoint not on priority list, no data to show.