Disorders of refraction and accommodation

H7_REFRAACCOMMODIS

obsolete_refractive error: ['Deviations from the average or standard indices of refraction of the eye through its dioptric or refractive apparatus.']

Endpoint definition

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FinnGen phenotype data

392423 individuals

Apply sex-specific rule None

392423

Check conditions None

392423

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H52

Cause of death: ICD-10 H52

2 out of 7 registries used, show all original rules.

7777

Check minimum number of events None

7777

Include endpoints

H7_HYPERMETRO

H7_MYOPIA

H7_ASTIGMATISM

H7_ANISOMETROPIA

H7_PRESBYOPIA

H7_ACCOMMODIS

H7_REFRADISNAS

8108

Remove individuals based on genotype QC

7737

H7_REFRAACCOMMODIS

Control definitions

Control exclude H7_OCUMUSCLE

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 H49-H52

Name in latin Perturbationes refractionis et accommodationis (oculi)

NAME	H7_REFRAACCOMMODIS
CONTROL_EXCLUDE	H7_OCUMUSCLE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	H7_HYPERMETRO\|H7_MYOPIA\|H7_ASTIGMATISM\|H7_ANISOMETROPIA\|H7_PRESBYOPIA\|H7_ACCOMMODIS\|H7_REFRADISNAS
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	H52
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	H52
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Or the full data table

Similar endpoints

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List of similar endpoints to Disorders of refraction and accommodation based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	7737	5056	2681
Unadjusted prevalence (%)	2.05	2.40	1.61
Mean age at first event (years)	42.73	41.45	45.14

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	1.97 [1.36, 2.85]	3.6e-4	301
15 years	0.01	1.27 [0.87, 1.86]	2.1e-1	152
5 years	0.00	1.98 [1.34, 2.93]	5.8e-4	76
1 year	0.00	4.08 [2.57, 6.49]	2.7e-9	29

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_REFRAACCOMMODIS – Disorders of refraction and accommodation
GWS hits:

Survival analyses between endpoints

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Plot

before Disorders of refraction and accommodation
after Disorders of refraction and accommodation

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Table

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Drugs most likely to be purchased after Disorders of refraction and accommodation

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Endpoint not on priority list, no data to show.

≡ Risteys

R9

R8

R7

R6

R5

R4

R3