Myopia

H7_MYOPIA

obsolete_myopia: ['A refractive error in which rays of light entering the EYE parallel to the optic axis are brought to a focus in front of the RETINA when accommodation (ACCOMMODATION, OCULAR) is relaxed. This results from an overly curved CORNEA or from the eyeball being too long from front to back. It is also called nearsightedness.']

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H52.1
Hospital discharge: ICD-9 3671
Hospital discharge: ICD-8 37002
Cause of death: ICD-10 H52.1
Cause of death: ICD-9 3671
Cause of death: ICD-8 37002

2 out of 7 registries used, show all original rules.

3702

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Check minimum number of events None

3702

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Include endpoints None

3702

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Remove individuals based on genotype QC

3534

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H7_MYOPIA

Control definitions

Control exclude H7_OCUMUSCLE

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H52
Name in latin Myopia

Summary Statistics

Key figures

All Female Male
Number of individuals 3534 2413 1121
Unadjusted prevalence (%) 0.94 1.14 0.67
Mean age at first event (years) 39.16 38.48 40.61

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.20 [0.53, 2.71] 6.6e-1 103
15 years 0.01 1.08 [0.55, 2.14] 8.1e-1 49
5 years 0.00 2.25 [1.27, 4.01] 5.8e-3 27
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_MYOPIA – Myopia
GWS hits: 5

Survival analyses between endpoints

Plot

before Myopia
after Myopia

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Myopia

Endpoint not on priority list, no data to show.