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Astigmatism

DOID EFO MESH PheWeb

H7_ASTIGMATISM

obsolete_astigmatism: ['Unequal curvature of the refractive surfaces of the eye. Thus a point source of light cannot be brought to a point focus on the retina but is spread over a more or less diffuse area. This results from the radius of curvature in one plane being longer or shorter than the radius at right angles to it. (Dorland, 27th ed).']

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H52.2
Hospital discharge: ICD-9 3672
Hospital discharge: ICD-8 37000
Cause of death: ICD-10 H52.2
Cause of death: ICD-9 3672
Cause of death: ICD-8 37000

2 out of 7 registries used, show all original rules.

1616

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Check minimum number of events None

1616

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Include endpoints None

1616

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Remove individuals based on genotype QC

1502

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H7_ASTIGMATISM

Control definitions

Control exclude H7_OCUMUSCLE

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H52
Name in latin Astigmatismus

Summary Statistics

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Key figures

All Female Male
Number of individuals 1502 848 654
Unadjusted prevalence (%) 0.40 0.40 0.39
Mean age at first event (years) 42.07 38.93 46.15

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.45 [1.33, 4.49] 3.8e-3 62
15 years 0.01 1.75 [0.96, 3.21] 6.9e-2 36
5 years 0.00 1.87 [0.93, 3.77] 7.9e-2 16
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_ASTIGMATISM – Astigmatism
GWS hits:

Survival analyses between endpoints

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Plot

before Astigmatism
after Astigmatism

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Astigmatism

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Endpoint not on priority list, no data to show.