Disorders of choroid and retina

H7_CHOROIDRETINA

retinopathy: Any disease or disorder of the retina.

Endpoint definition

FinnGen phenotype data

392423 individuals

diagram downward connector

Apply sex-specific rule None

392423

diagram downward connector

Check conditions None

392423

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H30-H36
Cause of death: ICD-10 H30-H36

2 out of 7 registries used, show all original rules.

33074

diagram downward connector

Check minimum number of events None

33074

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

32708

diagram downward connector
H7_CHOROIDRETINA

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

Summary Statistics

Key figures

All Female Male
Number of individuals 32708 16335 16373
Unadjusted prevalence (%) 8.67 7.75 9.85
Mean age at first event (years) 62.04 61.31 62.77

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.17 [1.89, 2.50] 3.0e-27 4577
15 years 0.01 1.41 [1.27, 1.58] 3.7e-10 2224
5 years 0.00 2.34 [2.13, 2.57] 4.4e-70 1458
1 year 0.00 3.22 [2.81, 3.69] 9.0e-64 404

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_CHOROIDRETINA – Disorders of choroid and retina
GWS hits: 9

Survival analyses between endpoints

Plot

before Disorders of choroid and retina
after Disorders of choroid and retina

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Disorders of choroid and retina

Endpoint not on priority list, no data to show.