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Retinal detachments and breaks

DOID EFO MESH SNOMED PheWeb

H7_RETINALDETACH

retinal detachment: An eye emergency condition which may lead to blindness if left untreated. It is characterized by the separation of the inner retina layers from the underlying pigment epithelium. Causes include trauma, advanced diabetes mellitus, high myopia, and choroid tumors. Symptoms include sudden appearance of floaters, sudden light flushes, and blurred vision.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

11585

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Remove individuals based on genotype QC

11230

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H7_RETINALDETACH

Control definitions

Control exclude H7_CHOROIDRETINA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

No data for upset plot.

No data for upset table.

Similar endpoints

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List of similar endpoints to Retinal detachments and breaks based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 11230 5447 5783
Unadjusted prevalence (%) 2.98 2.58 3.48
Mean age at first event (years) 61.54 60.03 62.97

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.21 [0.87, 1.68] 2.6e-1 1237
15 years 0.01 0.88 [0.69, 1.12] 3.1e-1 606
5 years 0.00 1.83 [1.51, 2.21] 4.0e-10 386
1 year 0.00 2.80 [2.19, 3.58] 2.7e-16 110

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_RETINALDETACH – Retinal detachments and breaks
GWS hits: 2

Survival analyses between endpoints

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Plot

before Retinal detachments and breaks
after Retinal detachments and breaks

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Retinal detachments and breaks

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Endpoint not on priority list, no data to show.