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Ovarian dysfunction: estrogen excess

DOID EFO MESH PheWeb

E4_ODESTRO

hyperestrogenism: ['Abnormally high level of estrogen. [ NICHD NCI ]']

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule

Sex only females

219462

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Check conditions None

219462

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E28.0#
Hospital discharge: ICD-9 2560
Hospital discharge: ICD-8 2560
Cause of death: ICD-10 E28.0#
Cause of death: ICD-9 2560
Cause of death: ICD-8 2560

2 out of 7 registries used, show all original rules.

37

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Check minimum number of events None

37

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Include endpoints None

37

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Remove individuals based on genotype QC

36

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E4_ODESTRO

Control definitions

Control exclude E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E28
Name in latin Hypersecretio oestrogenorum

Summary Statistics

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Key figures

All Female Male
Number of individuals 36 36 -
Unadjusted prevalence (%) 0.01 0.02 -
Mean age at first event (years) 32.98 32.98 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_ODESTRO – Ovarian dysfunction: estrogen excess
GWS hits:

Survival analyses between endpoints

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Plot

before Ovarian dysfunction: estrogen excess
after Ovarian dysfunction: estrogen excess

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Ovarian dysfunction: estrogen excess

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Endpoint not on priority list, no data to show.