obesity: A disorder involving an excessive amount of body fat.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E66
Cause of death: ICD-10 E66

2 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Remove individuals based on genotype QC


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Control definitions

Control exclude E4_OBESITY_HYPER

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E65-E68
Name in latin Obesitas

Similar endpoints

List of similar endpoints to Obesity based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 21375 14015 7360
Unadjusted prevalence (%) 5.67 6.65 4.43
Mean age at first event (years) 48.98 46.69 53.35


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.74 [3.05, 4.59] 9.4e-37 1587
15 years 0.01 2.10 [1.72, 2.56] 1.7e-13 660
5 years 0.00 4.30 [3.65, 5.07] 2.3e-67 428
1 year 0.00 14.49 [12.07, 17.41] <1e-100 274

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: E4_OBESITY – Obesity
GWS hits: 39

Survival analyses between endpoints


before Obesity
after Obesity

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