Obesity

DOID EFO MESH SNOMED PheWeb

E4_OBESITY

obesity: A disorder involving an excessive amount of body fat.

Endpoint definition

↥

FinnGen phenotype data

392423 individuals

Apply sex-specific rule None

392423

Check conditions None

392423

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E66

Cause of death: ICD-10 E66

2 out of 7 registries used, show all original rules.

21354

Check minimum number of events None

21354

Include endpoints

E4_OBESITYCAL

E4_OBESITYDRUG

E4_OBESITYXTRMALV

E4_OBESITYNAS

22148

Remove individuals based on genotype QC

21375

E4_OBESITY

Control definitions

Control exclude E4_OBESITY_HYPER

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF2

Parent code in ICD-10 E65-E68

Name in latin Obesitas

NAME	E4_OBESITY
CONTROL_EXCLUDE	E4_OBESITY_HYPER
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	E4_OBESITYCAL\|E4_OBESITYDRUG\|E4_OBESITYXTRMALV\|E4_OBESITYNAS
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	E66
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	E66
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Show upset plot detailing case counts by codes

Or the full data table

Similar endpoints

↥

List of similar endpoints to Obesity based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

↥

Key figures

	All	Female	Male
Number of individuals	21375	14015	7360
Unadjusted prevalence (%)	5.67	6.65	4.43
Mean age at first event (years)	48.98	46.69	53.35

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	3.74 [3.05, 4.59]	9.4e-37	1587
15 years	0.01	2.10 [1.72, 2.56]	1.7e-13	660
5 years	0.00	4.30 [3.65, 5.07]	2.3e-67	428
1 year	0.00	14.49 [12.07, 17.41]	<1e-100	274

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: E4_OBESITY – Obesity
GWS hits: 39

Survival analyses between endpoints

↥

Plot

before Obesity
after Obesity

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Obesity

↥

≡ Risteys

R9

R8

R7

R6

R5

R4

R3