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Obesity due to excess calories

DOID EFO MESH SNOMED PheWeb

E4_OBESITYCAL

obesity: A disorder involving an excessive amount of body fat.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E66.00, E66.01
Cause of death: ICD-10 E66.00, E66.01

2 out of 7 registries used, show all original rules.

15608

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Check minimum number of events None

15608

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Include endpoints None

15608

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Remove individuals based on genotype QC

15045

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E4_OBESITYCAL

Control definitions

Control exclude E4_OBESITY

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 15045 9746 5299
Unadjusted prevalence (%) 3.99 4.62 3.19
Mean age at first event (years) 50.06 47.45 54.87

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 4.36 [3.34, 5.70] 4.4e-27 955
15 years 0.02 2.46 [1.93, 3.13] 3.2e-13 410
5 years 0.01 5.35 [4.33, 6.61] 1.3e-54 303
1 year 0.00 13.86 [10.94, 17.56] <1e-100 149

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_OBESITYCAL – Obesity due to excess calories
GWS hits: 26

Survival analyses between endpoints

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Plot

before Obesity due to excess calories
after Obesity due to excess calories

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Obesity due to excess calories

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Endpoint not on priority list, no data to show.