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Extreme obesity with alveolar hypoventilation

DOID EFO MESH SNOMED PheWeb

E4_OBESITYXTRMALV

obesity: A disorder involving an excessive amount of body fat.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E66.2
Hospital discharge: ICD-9 2788A
Cause of death: ICD-10 E66.2
Cause of death: ICD-9 2788A

2 out of 7 registries used, show all original rules.

1093

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Check minimum number of events None

1093

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Include endpoints None

1093

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Remove individuals based on genotype QC

1064

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E4_OBESITYXTRMALV

Control definitions

Control exclude E4_OBESITY

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E66
Name in latin Obesitas extrema cum hypoventilatione alveolari

Summary Statistics

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Key figures

All Female Male
Number of individuals 1064 602 462
Unadjusted prevalence (%) 0.28 0.29 0.28
Mean age at first event (years) 58.42 56.93 60.35

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.27 20.74 [13.62, 31.56] 2.0e-45 180
15 years 0.03 5.36 [3.40, 8.43] 4.4e-13 46
5 years 0.02 17.42 [12.43, 24.42] 8.6e-62 70
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_OBESITYXTRMALV – Extreme obesity with alveolar hypoventilation
GWS hits: 1

Survival analyses between endpoints

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Plot

before Extreme obesity with alveolar hypoventilation
after Extreme obesity with alveolar hypoventilation

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Drugs most likely to be purchased after Extreme obesity with alveolar hypoventilation

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Endpoint not on priority list, no data to show.