Extreme obesity with alveolar hypoventilation

E4_OBESITYXTRMALV

obesity: A disorder involving an excessive amount of body fat.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E66.2
Hospital discharge: ICD-9 2788A
Cause of death: ICD-10 E66.2
Cause of death: ICD-9 2788A

2 out of 7 registries used, show all original rules.

1093

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Check minimum number of events None

1093

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Include endpoints None

1093

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Remove individuals based on genotype QC

1064

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E4_OBESITYXTRMALV

Control definitions

Control exclude E4_OBESITY

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E66
Name in latin Obesitas extrema cum hypoventilatione alveolari

Summary Statistics

Key figures

All Female Male
Number of individuals 1064 602 462
Unadjusted prevalence (%) 0.28 0.29 0.28
Mean age at first event (years) 58.42 56.93 60.35

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.27 20.74 [13.62, 31.56] 2.0e-45 180
15 years 0.03 5.36 [3.40, 8.43] 4.4e-13 46
5 years 0.02 17.42 [12.43, 24.42] 8.6e-62 70
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: E4_OBESITYXTRMALV – Extreme obesity with alveolar hypoventilation
GWS hits: 1

Survival analyses between endpoints

Plot

before Extreme obesity with alveolar hypoventilation
after Extreme obesity with alveolar hypoventilation

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Extreme obesity with alveolar hypoventilation

Endpoint not on priority list, no data to show.