Obesity, other/unspecified


obesity: A disorder involving an excessive amount of body fat.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E66.8, E66.9
Hospital discharge: ICD-9 2780
Hospital discharge: ICD-8 27799
Cause of death: ICD-10 E66.8, E66.9
Cause of death: ICD-9 2780
Cause of death: ICD-8 27799

2 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Include endpoints None


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Remove individuals based on genotype QC


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Control definitions

Control exclude E4_OBESITY

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 11025 7586 3439
Unadjusted prevalence (%) 2.92 3.60 2.07
Mean age at first event (years) 47.35 45.73 50.92


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.99 [3.16, 5.04] 2.0e-31 901
15 years 0.01 2.28 [1.90, 2.75] 3.3e-18 354
5 years 0.01 4.47 [3.72, 5.37] 2.7e-57 225
1 year 0.00 18.18 [14.76, 22.40] <1e-100 174

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: E4_OBESITYNAS – Obesity, other/unspecified
GWS hits: 16

Survival analyses between endpoints


before Obesity, other/unspecified
after Obesity, other/unspecified

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Drugs most likely to be purchased after Obesity, other/unspecified

Endpoint not on priority list, no data to show.