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Other and unspecified diseases of blood and blood-forming organs

DOID EFO MESH SNOMED PheWeb

D3_BLOODNAS

hematologic disease: A disease involving the hematopoietic system.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 D75.8, D75.9
Hospital discharge: ICD-9 289[8-9]
Hospital discharge: ICD-8 2899
Hospital discharge: excluded ICD-8 2899[0-1]
Cause of death: ICD-10 D75.8, D75.9
Cause of death: ICD-9 289[8-9]
Cause of death: ICD-8 2899
Cause of death: excluded ICD-8 2899[0-1]

2 out of 7 registries used, show all original rules.

651

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Check minimum number of events None

651

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Include endpoints None

651

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Remove individuals based on genotype QC

633

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D3_BLOODNAS

Control definitions

Control exclude D3_BLOODOTHER

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other and unspecified diseases of blood and blood-forming organs based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 633 328 305
Unadjusted prevalence (%) 0.17 0.16 0.18
Mean age at first event (years) 55.76 53.86 57.79

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.69 [1.91, 7.13] 1.0e-4 106
15 years 0.01 1.93 [0.96, 3.85] 6.4e-2 45
5 years 0.00 3.62 [2.16, 6.07] 1.1e-6 29
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: D3_BLOODNAS – Other and unspecified diseases of blood and blood-forming organs
GWS hits: 1

Survival analyses between endpoints

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Plot

before Other and unspecified diseases of blood and blood-forming organs
after Other and unspecified diseases of blood and blood-forming organs

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Drugs most likely to be purchased after Other and unspecified diseases of blood and blood-forming organs

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Endpoint not on priority list, no data to show.