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Alzheimer’s disease (Late onset) (more control exclusions)

PheWeb

AD_LO_EXMORE

No definition available.

Endpoint definition

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FinnGen phenotype data

individuals

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Apply sex-specific rule None

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Check conditions None

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F00.1*, F00.10*, F00.10*G30.1, G30.1, G30.1+F00.10
Cause of death: ICD-10 F00.1*, F00.10*, F00.10*G30.1, G30.1, G30.1+F00.10

2 out of 7 registries used, show all original rules.

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Check minimum number of events None

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Include endpoints None

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Remove individuals based on genotype QC

6489

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AD_LO_EXMORE

Control definitions

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 6489 2946 3543
Unadjusted prevalence (%) 1.72 1.40 2.13
Mean age at first event (years) 79.83 80.00 79.68

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.12 7.30 [5.85, 9.10] 8.0e-70 3584
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: AD_LO_EXMORE – Alzheimer’s disease (Late onset) (more control exclusions)
GWS hits: 11

Survival analyses between endpoints

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Plot

before Alzheimer’s disease (Late onset) (more control exclusions)
after Alzheimer’s disease (Late onset) (more control exclusions)

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Alzheimer’s disease (Late onset) (more control exclusions)

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Endpoint not on priority list, no data to show.