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Memory loss

DOID MESH PheWeb

MEMLOSS

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 R41.1, R41.2, R41.3
Cause of death: ICD-10 R41.1, R41.2, R41.3

2 out of 7 registries used, show all original rules.

2599

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Check minimum number of events None

2599

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Include endpoints None

2599

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Remove individuals based on genotype QC

2526

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MEMLOSS

Control definitions

Control exclude F5_DEMENTIA, G6_ALZHEIMER, G6_AD_WIDE

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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Summary Statistics

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Key figures

All Female Male
Number of individuals 2526 1322 1204
Unadjusted prevalence (%) 0.67 0.63 0.72
Mean age at first event (years) 66.21 65.03 67.51

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.04 [2.18, 4.22] 4.5e-11 397
15 years 0.01 1.45 [1.04, 2.01] 2.8e-2 157
5 years 0.00 3.64 [2.79, 4.75] 1.8e-21 167
1 year 0.00 6.51 [4.69, 9.05] 5.9e-29 60

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: MEMLOSS – Memory loss
GWS hits: 1

Survival analyses between endpoints

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Plot

before Memory loss
after Memory loss

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Memory loss

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Endpoint not on priority list, no data to show.