Alzheimer’s disease (Atypical or mixed) (more control exclusions)

AD_AM_EXMORE

No definition available.

Endpoint definition

FinnGen phenotype data

individuals

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Apply sex-specific rule None

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Check conditions None

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F00.24*, G30.8, G30.8+F00.20
Cause of death: ICD-10 F00.24*, G30.8, G30.8+F00.20

2 out of 7 registries used, show all original rules.

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Check minimum number of events None

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Include endpoints None

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Remove individuals based on genotype QC

2044

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AD_AM_EXMORE

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 2044 794 1250
Unadjusted prevalence (%) 0.54 0.38 0.75
Mean age at first event (years) 80.77 81.32 80.42

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.21 15.62 [13.14, 18.58] <1e-100 1124
15 years 0.01 2.24 [1.83, 2.74] 3.7e-15 154
5 years 0.01 8.99 [7.39, 10.93] <1e-100 520
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: AD_AM_EXMORE – Alzheimer’s disease (Atypical or mixed) (more control exclusions)
GWS hits: 1

Survival analyses between endpoints

Plot

before Alzheimer’s disease (Atypical or mixed) (more control exclusions)
after Alzheimer’s disease (Atypical or mixed) (more control exclusions)

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Alzheimer’s disease (Atypical or mixed) (more control exclusions)

Endpoint not on priority list, no data to show.