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Vascular dementia (subcortical)

DOID EFO MESH SNOMED PheWeb

VD_SC

vascular dementia: A degenerative vascular disorder affecting the brain. It is caused by the blockage of the blood supply to the brain. It is manifested with decline of memory and cognitive functions.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F01.2
Cause of death: ICD-10 F01.2

2 out of 7 registries used, show all original rules.

658

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Check minimum number of events None

658

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Include endpoints None

658

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Remove individuals based on genotype QC

636

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VD_SC

Control definitions

Control exclude F5_DEMENTIA, G6_ALZHEIMER, G6_AD_WIDE

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 F01
Name in latin Dementia vascularis subcorticalis

Summary Statistics

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Key figures

All Female Male
Number of individuals 636 235 401
Unadjusted prevalence (%) 0.17 0.11 0.24
Mean age at first event (years) 79.30 80.94 78.34

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: VD_SC – Vascular dementia (subcortical)
GWS hits: 2

Survival analyses between endpoints

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Plot

before Vascular dementia (subcortical)
after Vascular dementia (subcortical)

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Vascular dementia (subcortical)

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Endpoint not on priority list, no data to show.