Rheumatoid lung disease

RHEUMAT_LUNG

adult-onset Still's disease: adult-onset Still disease (AOSD) is a rare inflammatory multisystem disorder characterized clinically by fever of unknown origin, arthralgia or arthritis, hyperleucocytosis, and typical skin rash.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 J99.0*, J99.0*M05.1, M05.1+J99.0
Cause of death: ICD-10 J99.0*, J99.0*M05.1, M05.1+J99.0

2 out of 7 registries used, show all original rules.

91

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Check minimum number of events None

91

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Include endpoints None

91

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Remove individuals based on genotype QC

89

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RHEUMAT_LUNG

Control definitions

Control exclude ILD_SYST_AUTO_DISEASES

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 89 39 50
Unadjusted prevalence (%) 0.02 0.02 0.03
Mean age at first event (years) 68.04 65.49 70.04

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: RHEUMAT_LUNG – Rheumatoid lung disease
GWS hits: 1

Survival analyses between endpoints

Plot

before Rheumatoid lung disease
after Rheumatoid lung disease

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Rheumatoid lung disease

Endpoint not on priority list, no data to show.