Osteoporosis with pathological fracture (FG)

OSTEOPOROSIS_FRACTURE_FG

No definition available.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Remove individuals based on genotype QC

1659

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OSTEOPOROSIS_FRACTURE_FG

Control definitions

Control exclude RHEUMA_ENDPOINTS

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 1659 1557 102
Unadjusted prevalence (%) 0.44 0.74 0.06
Mean age at first event (years) 70.80 71.16 65.29

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.14 10.15 [7.92, 13.01] 6.7e-75 280
15 years 0.02 3.33 [2.53, 4.37] 5.4e-18 90
5 years 0.01 6.88 [5.19, 9.12] 5.6e-41 122
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: OSTEOPOROSIS_FRACTURE_FG – Osteoporosis with pathological fracture (FG)
GWS hits: 2

Survival analyses between endpoints

Plot

before Osteoporosis with pathological fracture (FG)
after Osteoporosis with pathological fracture (FG)

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Drugs most likely to be purchased after Osteoporosis with pathological fracture (FG)

Endpoint not on priority list, no data to show.