Diseases of male genital organs

N14_MALEGEN

male reproductive organ cancer: A reproductive organ cancer that is manifested in the male genital system. This includes organs such as the penis and scrotum.

Endpoint definition

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FinnGen phenotype data

392423 individuals

Apply sex-specific rule

Sex only males

172961

Check conditions None

172961

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 N40-N51

Cause of death: ICD-10 N40-N51

2 out of 7 registries used, show all original rules.

42976

Check minimum number of events None

42976

Include endpoints

N14_PROSTHYPERPLA

N14_PROSTATITIS

N14_PROSTAOTH

N14_HYDROCELE

N14_SPERMATOCELE

N14_TORSIOTEST

N14_ORHCEPINDIDYMITIS

N14_MALEINFERT

N14_PHIMOSIS

N14_IMPOTENCE

N14_OTHPENIS

N14_INFLAMALEGEN

N14_OTHDISMALEGEN

N14_MALEGENINOTH

48716

Remove individuals based on genotype QC

47110

N14_MALEGEN

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

NAME	N14_MALEGEN
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX	1
INCLUDE	N14_PROSTHYPERPLA\|N14_PROSTATITIS\|N14_PROSTAOTH\|N14_HYDROCELE\|N14_SPERMATOCELE\|N14_TORSIOTEST\|N14_ORHCEPINDIDYMITIS\|N14_MALEINFERT\|N14_PHIMOSIS\|N14_IMPOTENCE\|N14_OTHPENIS\|N14_INFLAMALEGEN\|N14_OTHDISMALEGEN\|N14_MALEGENINOTH
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	N[4-5]
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	N[4-5]
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Or the full data table

Similar endpoints

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List of similar endpoints to Diseases of male genital organs based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	47110	-	47110
Unadjusted prevalence (%)	12.49	-	28.33
Mean age at first event (years)	57.13	-	57.13

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	2.20 [1.98, 2.44]	2.7e-49	9296
15 years	0.01	1.51 [1.38, 1.65]	1.1e-19	4355
5 years	0.00	2.55 [2.36, 2.75]	<1e-100	2543
1 year	0.00	4.72 [4.23, 5.27]	<1e-100	925

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: N14_MALEGEN – Diseases of male genital organs
GWS hits: 19

Survival analyses between endpoints

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Plot

before Diseases of male genital organs
after Diseases of male genital organs

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Table

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Drugs most likely to be purchased after Diseases of male genital organs

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Endpoint not on priority list, no data to show.

≡ Risteys

R9

R8

R7

R6

R5

R4

R3