Male infertility

N14_MALEINFERT

male infertility: The inability of the male to effect fertilization of an ovum after a specified period of unprotected intercourse. Male sterility is permanent infertility.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule

Sex only males

172961

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Check conditions None

172961

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 N46
Hospital discharge: ICD-9 606
Hospital discharge: ICD-8 606
Cause of death: ICD-10 N46
Cause of death: ICD-9 606
Cause of death: ICD-8 606

2 out of 7 registries used, show all original rules.

1367

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Check minimum number of events None

1367

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Include endpoints None

1367

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Remove individuals based on genotype QC

1271

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N14_MALEINFERT

Control definitions

Control exclude N14_MALEGEN

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 N40-N51
Name in latin Infertilitas masculina

Summary Statistics

Key figures

All Female Male
Number of individuals 1271 - 1271
Unadjusted prevalence (%) 0.34 - 0.76
Mean age at first event (years) 34.61 - 34.61

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.65 [1.23, 5.69] 1.2e-2 25
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: N14_MALEINFERT – Male infertility
GWS hits: 1

Survival analyses between endpoints

Plot

before Male infertility
after Male infertility

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Male infertility

Endpoint not on priority list, no data to show.