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Redundant prepuce, phimosis and paraphimosis

DOID EFO MESH SNOMED PheWeb

N14_PHIMOSIS

phimosis: A condition in which there is constriction in the tip of the foreskin resulting in inability to fully retract the foreskin over the glans penis. Causes include balanoposthitis, balanitis xerotica obliterans, and untreated diabetes.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule

Sex only males

172961

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Check conditions None

172961

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 N47
Hospital discharge: ICD-9 605
Hospital discharge: ICD-8 605
Cause of death: ICD-10 N47
Cause of death: ICD-9 605
Cause of death: ICD-8 605

2 out of 7 registries used, show all original rules.

7058

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Check minimum number of events None

7058

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Include endpoints None

7058

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Remove individuals based on genotype QC

6859

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N14_PHIMOSIS

Control definitions

Control exclude N14_MALEGEN

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 N40-N51
Name in latin Praeputium redundans, phimosis sive paraphimosis

Summary Statistics

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Key figures

All Female Male
Number of individuals 6859 - 6859
Unadjusted prevalence (%) 1.82 - 4.13
Mean age at first event (years) 36.05 - 36.05

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.18 [2.05, 4.94] 2.7e-7 580
15 years 0.01 1.76 [1.19, 2.62] 4.8e-3 223
5 years 0.00 3.98 [2.86, 5.53] 2.6e-16 190
1 year 0.00 8.09 [5.71, 11.47] 8.3e-32 87

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: N14_PHIMOSIS – Redundant prepuce, phimosis and paraphimosis
GWS hits: 2

Survival analyses between endpoints

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Plot

before Redundant prepuce, phimosis and paraphimosis
after Redundant prepuce, phimosis and paraphimosis

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Drugs most likely to be purchased after Redundant prepuce, phimosis and paraphimosis

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Endpoint not on priority list, no data to show.