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Macular cyst

DOID EFO MESH SNOMED PheWeb

MACULAR_CYST

age-related macular degeneration: Age-related loss of vision in the central portion of the retina (macula), secondary to retinal degeneration.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H35.36#
Hospital discharge: ICD-9 3625C
Cause of death: ICD-10 H35.36#
Cause of death: ICD-9 3625C

2 out of 7 registries used, show all original rules.

512

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Check minimum number of events None

512

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Include endpoints None

512

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Remove individuals based on genotype QC

491

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MACULAR_CYST

Control definitions

Control exclude H7_CHOROIDRETINA

Extra metadata

Level in the ICD hierarchy 5
First used in FinnGen datafreeze DF4
Parent code in ICD-10 H35

Summary Statistics

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Key figures

All Female Male
Number of individuals 491 270 221
Unadjusted prevalence (%) 0.13 0.13 0.13
Mean age at first event (years) 70.63 70.72 70.53

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.76 [1.01, 7.56] 4.8e-2 21
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: MACULAR_CYST – Macular cyst
GWS hits: 2

Survival analyses between endpoints

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Plot

before Macular cyst
after Macular cyst

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Macular cyst

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Endpoint not on priority list, no data to show.