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Disorders of synovium and tendon

DOID EFO MESH SNOMED PheWeb

M13_SYNOTEND

Tendinopathy: Disorders that are causes by overuse of tendons.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M65-M68
Cause of death: ICD-10 M65-M68

2 out of 7 registries used, show all original rules.

18231

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Check minimum number of events None

18231

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Include endpoints

21209

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Remove individuals based on genotype QC

20492

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M13_SYNOTEND

Control definitions

Control exclude M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Disorders of synovium and tendon based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 20492 13649 6843
Unadjusted prevalence (%) 5.43 6.47 4.12
Mean age at first event (years) 48.06 47.13 49.92

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.02 [0.83, 1.26] 8.3e-1 939
15 years 0.00 0.80 [0.66, 0.97] 2.4e-2 457
5 years 0.00 0.95 [0.76, 1.18] 6.3e-1 149
1 year 0.00 1.47 [1.04, 2.07] 2.7e-2 42

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_SYNOTEND – Disorders of synovium and tendon
GWS hits: 2

Survival analyses between endpoints

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Plot

before Disorders of synovium and tendon
after Disorders of synovium and tendon

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Disorders of synovium and tendon

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Endpoint not on priority list, no data to show.