Radial styloid tenosynovitis [de Quervain]

M13_DEQUERVAIN

De Quervain disease: Stenosing tenosynovitis of the abductor pollicis longus and extensor pollicis brevis tendons in the first dorsal wrist compartment. The presenting symptoms are usually pain and tenderness at the radial styloid. The cause is almost always related to overuse injury or is associated with rheumatoid arthritis.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M65.4
Hospital discharge: ICD-9 7270A
Cause of death: ICD-10 M65.4
Cause of death: ICD-9 7270A

2 out of 7 registries used, show all original rules.

1608

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Check minimum number of events None

1608

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Include endpoints None

1608

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Remove individuals based on genotype QC

1552

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M13_DEQUERVAIN

Control definitions

Control exclude M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M65
Name in latin Tenosynovitis regionis processus styloidis radii (de Quervain)

Summary Statistics

Key figures

All Female Male
Number of individuals 1552 1269 283
Unadjusted prevalence (%) 0.41 0.60 0.17
Mean age at first event (years) 46.71 46.36 48.24

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.67 [0.59, 4.73] 3.3e-1 39
15 years 0.01 1.57 [0.67, 3.67] 3.0e-1 21
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: M13_DEQUERVAIN – Radial styloid tenosynovitis [de Quervain]
GWS hits: 1

Survival analyses between endpoints

Plot

before Radial styloid tenosynovitis [de Quervain]
after Radial styloid tenosynovitis [de Quervain]

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Radial styloid tenosynovitis [de Quervain]

Endpoint not on priority list, no data to show.