Soft tissue disorders


musculoskeletal system disease: A disease involving the musculoskeletal system. [database_cross_reference: MONDO:DesignPattern]

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M60-M79
Cause of death: ICD-10 M60-M79

2 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Remove individuals based on genotype QC


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Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Soft tissue disorders based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 102065 60310 41755
Unadjusted prevalence (%) 27.07 28.61 25.11
Mean age at first event (years) 51.22 49.51 53.68


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.19 [1.07, 1.33] 1.1e-3 7417
15 years 0.01 0.90 [0.82, 0.99] 2.4e-2 3438
5 years 0.00 1.55 [1.43, 1.69] 2.5e-24 1623
1 year 0.00 3.18 [2.83, 3.59] 2.3e-80 624

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: M13_SOFTTISSUE – Soft tissue disorders
GWS hits: 15

Survival analyses between endpoints


before Soft tissue disorders
after Soft tissue disorders

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Drugs most likely to be purchased after Soft tissue disorders

Endpoint not on priority list, no data to show.