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Spinal stenosis

DOID EFO MESH SNOMED PheWeb

M13_SPINSTENOSIS

spinal stenosis: Narrowing of the spinal canal.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M48.0
Hospital discharge: ICD-9 7230A|7240
Cause of death: ICD-10 M48.0
Cause of death: ICD-9 7230A|7240

2 out of 7 registries used, show all original rules.

19463

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Check minimum number of events None

19463

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Include endpoints None

19463

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Remove individuals based on genotype QC

18989

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M13_SPINSTENOSIS

Control definitions

Control exclude M13_DORSOPATHY

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M48
Name in latin Stenosis spinalis

Summary Statistics

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Key figures

All Female Male
Number of individuals 18989 9976 9013
Unadjusted prevalence (%) 5.04 4.73 5.42
Mean age at first event (years) 64.23 63.85 64.66

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.67 [1.42, 1.97] 9.3e-10 2244
15 years 0.01 1.15 [0.99, 1.33] 6.0e-2 1178
5 years 0.00 1.83 [1.61, 2.09] 7.8e-20 606
1 year 0.00 2.83 [2.35, 3.42] 2.8e-27 172

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_SPINSTENOSIS – Spinal stenosis
GWS hits: 35

Survival analyses between endpoints

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Plot

before Spinal stenosis
after Spinal stenosis

loading spinner Loading survival analyses plot