≡ Risteys
R9

Documentation Changelog GitHub Contact & Feedback

Disorders of muscles

DOID EFO MESH SNOMED PheWeb

M13_MUSCLE

myositis: An inflammatory disease involving a pathogenic inflammatory response in the muscle tissue.

Endpoint definition

↥
FinnGen phenotype data

392423 individuals

diagram downward connector

Apply sex-specific rule None

392423

diagram downward connector

Check conditions None

392423

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M60-M63
Cause of death: ICD-10 M60-M63

2 out of 7 registries used, show all original rules.

2565

diagram downward connector

Check minimum number of events None

2565

diagram downward connector
diagram bullet diagram downward connector

Include endpoints

3116

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

3008

diagram downward connector
M13_MUSCLE

Control definitions

Control exclude M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Similar endpoints

↥

List of similar endpoints to Disorders of muscles based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 3008 1599 1409
Unadjusted prevalence (%) 0.80 0.76 0.85
Mean age at first event (years) 49.74 48.07 51.64

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.53 [0.45, 5.24] 5.0e-1 286
15 years 0.01 1.09 [0.40, 2.93] 8.7e-1 108
5 years 0.00 2.76 [1.37, 5.57] 4.6e-3 74
1 year 0.00 10.75 [5.62, 20.55] 7.1e-13 54

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: M13_MUSCLE – Disorders of muscles
GWS hits: 1

Survival analyses between endpoints

↥

Plot

before Disorders of muscles
after Disorders of muscles

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Disorders of muscles

↥

Endpoint not on priority list, no data to show.