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Scoliosis

DOID EFO MESH SNOMED PheWeb

M13_SCOLIOSIS

scoliosis: A congenital or acquired spinal deformity characterized by lateral curvature of the spine.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M41
Hospital discharge: ICD-9 7373
Cause of death: ICD-10 M41
Cause of death: ICD-9 7373

2 out of 7 registries used, show all original rules.

2628

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Check minimum number of events None

2628

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Include endpoints None

2628

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Remove individuals based on genotype QC

2529

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M13_SCOLIOSIS

Control definitions

Control exclude M13_DORSOPATHY

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M40-M43
Name in latin Scoliosis

Summary Statistics

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Key figures

All Female Male
Number of individuals 2529 1986 543
Unadjusted prevalence (%) 0.67 0.94 0.33
Mean age at first event (years) 41.71 41.39 42.89

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.89 [1.72, 4.86] 6.3e-5 83
15 years 0.01 1.29 [0.73, 2.27] 3.7e-1 30
5 years 0.00 3.02 [1.85, 4.94] 1.0e-5 31
1 year 0.00 5.43 [2.72, 10.83] 1.6e-6 11

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_SCOLIOSIS – Scoliosis
GWS hits:

Survival analyses between endpoints

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Plot

before Scoliosis
after Scoliosis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Scoliosis

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Endpoint not on priority list, no data to show.