Panniculitis affecting regions of neck and back

M13_PANNICULITIS

panniculitis: a group of diseases whose hallmark is inflammation of subcutaneous adipose tissue (the fatty layer under the skin - panniculus adiposus). Symptoms include tender skin nodules, and systemic signs such as weight loss and fatigue.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M54.0
Cause of death: ICD-10 M54.0

2 out of 7 registries used, show all original rules.

1159

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Check minimum number of events None

1159

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Include endpoints None

1159

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Remove individuals based on genotype QC

1115

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M13_PANNICULITIS

Control definitions

Control exclude M13_DORSOPATHY

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M54
Name in latin Panniculitis dorsi

Summary Statistics

Key figures

All Female Male
Number of individuals 1115 688 427
Unadjusted prevalence (%) 0.30 0.33 0.26
Mean age at first event (years) 50.72 48.97 53.52

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.12 [1.79, 5.44] 6.2e-5 115
15 years 0.01 2.04 [1.22, 3.39] 6.3e-3 60
5 years 0.00 3.47 [2.25, 5.36] 1.7e-8 35
1 year 0.00 5.17 [2.61, 10.24] 2.5e-6 10

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: M13_PANNICULITIS – Panniculitis affecting regions of neck and back
GWS hits:

Survival analyses between endpoints

Plot

before Panniculitis affecting regions of neck and back
after Panniculitis affecting regions of neck and back

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Drugs most likely to be purchased after Panniculitis affecting regions of neck and back

Endpoint not on priority list, no data to show.