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Dorsalgia

DOID EFO MESH SNOMED PheWeb

M13_DORSALGIA

causalgia: Complex regional pain syndrome type 2 (CRPS2), or causalgia is a form of complex regional pain syndrome that develops after damage to a peripheral nerve and is characterized by spontaneous pain, allodynia and hyperalgesia , not necessarily limited to the territory of the injured nerve, as well as at some point, edema, changes in skin blood flow or sudomotor dysfunction in the pain area.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

61684

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Remove individuals based on genotype QC

59438

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M13_DORSALGIA

Control definitions

Control exclude M13_DORSOPATHY

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 59438 36585 22853
Unadjusted prevalence (%) 15.76 17.35 13.74
Mean age at first event (years) 50.81 49.53 52.87

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.94 [1.71, 2.19] 7.9e-25 5046
15 years 0.01 1.20 [1.08, 1.32] 5.0e-4 1972
5 years 0.00 2.60 [2.38, 2.84] 2.7e-100 1355
1 year 0.00 6.69 [5.95, 7.52] <1e-100 704

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_DORSALGIA – Dorsalgia
GWS hits: 18

Survival analyses between endpoints

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Plot

before Dorsalgia
after Dorsalgia

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Dorsalgia

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Endpoint not on priority list, no data to show.