Muscle wasting and atrophy, not elsewhere classified

DOID EFO MESH PheWeb

M13_MUSCLEATROPH

muscular disease: Acquired, familial, and congenital disorders of skeletal muscle and smooth muscle.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M62.5

Hospital discharge: ICD-9 7282A

Hospital discharge: ICD-8 7331

Cause of death: ICD-10 M62.5

Cause of death: ICD-9 7282A

Cause of death: ICD-8 7331

2 out of 7 registries used, show all original rules.

166

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Check minimum number of events None

166

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Include endpoints None

166

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Remove individuals based on genotype QC

163

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M13_MUSCLEATROPH

Control definitions

Control exclude M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 M62

Name in latin Atrophia et degeneratio musculi non alibi classificatae

NAME	M13_MUSCLEATROPH
CONTROL_EXCLUDE	M13_SOFTTISSUE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	M625
HD_ICD_9	7282A
HD_ICD_8	7331
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	M625
COD_ICD_9	7282A
COD_ICD_8	7331
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Similar endpoints

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List of similar endpoints to Muscle wasting and atrophy, not elsewhere classified based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	163	82	81
Unadjusted prevalence (%)	0.04	0.04	0.05
Mean age at first event (years)	55.71	52.50	58.96

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_MUSCLEATROPH – Muscle wasting and atrophy, not elsewhere classified
GWS hits:

Survival analyses between endpoints

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Plot

before Muscle wasting and atrophy, not elsewhere classified
after Muscle wasting and atrophy, not elsewhere classified

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Table

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Drugs most likely to be purchased after Muscle wasting and atrophy, not elsewhere classified

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Endpoint not on priority list, no data to show.