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Kyphosis

DOID EFO MESH SNOMED PheWeb

M13_KYPHOSIS

phimosis: A condition in which there is constriction in the tip of the foreskin resulting in inability to fully retract the foreskin over the glans penis. Causes include balanoposthitis, balanitis xerotica obliterans, and untreated diabetes.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M40.0, M40.1, M40.2
Hospital discharge: ICD-9 737[0-1]
Cause of death: ICD-10 M40.0, M40.1, M40.2
Cause of death: ICD-9 737[0-1]

2 out of 7 registries used, show all original rules.

325

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Check minimum number of events None

325

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Include endpoints None

325

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Remove individuals based on genotype QC

317

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M13_KYPHOSIS

Control definitions

Control exclude M13_DORSOPATHY

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 317 189 128
Unadjusted prevalence (%) 0.08 0.09 0.08
Mean age at first event (years) 57.85 58.94 56.23

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_KYPHOSIS – Kyphosis
GWS hits: 1

Survival analyses between endpoints

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Plot

before Kyphosis
after Kyphosis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Kyphosis

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Endpoint not on priority list, no data to show.