Chondropathies

DOID MESH PheWeb

M13_CHRONDROPATHIES

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M91-M94

Cause of death: ICD-10 M91-M94

2 out of 7 registries used, show all original rules.

3584

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Check minimum number of events None

3584

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Include endpoints

M13_JUVOSTEOCHONRHIP

M13_OSTEOCHONDROPATHY

M13_TIETZE

M13_RELAPSPOLYCHONDR

M13_CHONDROMALACIA

M13_CHONDROLYSIS

5015

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Remove individuals based on genotype QC

4850

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M13_CHRONDROPATHIES

Control definitions

Control exclude M13_OTHERBONE

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

NAME	M13_CHRONDROPATHIES
CONTROL_EXCLUDE	M13_OTHERBONE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	M13_JUVOSTEOCHONRHIP\|M13_OSTEOCHONDROPATHY\|M13_TIETZE\|M13_RELAPSPOLYCHONDR\|M13_CHONDROMALACIA\|M13_CHONDROLYSIS
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	M9[1-4]
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	M9[1-4]
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Show upset plot detailing case counts by codes

Or the full data table

Similar endpoints

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List of similar endpoints to Chondropathies based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	4850	2823	2027
Unadjusted prevalence (%)	1.29	1.34	1.22
Mean age at first event (years)	37.51	38.37	36.31

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.32 [0.79, 2.20]	2.9e-1	266
15 years	0.00	0.78 [0.48, 1.28]	3.3e-1	97
5 years	0.00	1.45 [0.91, 2.29]	1.2e-1	43
1 year	0.00	3.45 [2.01, 5.93]	7.1e-6	19

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_CHRONDROPATHIES – Chondropathies
GWS hits:

Survival analyses between endpoints

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Plot

before Chondropathies
after Chondropathies

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Table

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Drugs most likely to be purchased after Chondropathies

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Endpoint not on priority list, no data to show.