≡ Risteys
R9

Documentation Changelog GitHub Contact & Feedback

Coxarthrosis,

DOID EFO MESH PheWeb

M13_ARTHTROSIS_COX

osteoarthritis: A noninflammatory degenerative joint disease occurring chiefly in older persons, characterised by degeneration of the articular cartilage, hypertrophy of bone at the margins and changes in the synovial membrane. It is accompanied by pain and stiffness, particularly after prolonged activity.

Endpoint definition

↥
FinnGen phenotype data

392423 individuals

diagram downward connector

Apply sex-specific rule None

392423

diagram downward connector

Check conditions None

392423

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M16
Hospital discharge: ICD-9 7151E|7152E
Hospital discharge: ICD-8 71300
Cause of death: ICD-10 M16
Cause of death: ICD-9 7151E|7152E
Cause of death: ICD-8 71300

2 out of 7 registries used, show all original rules.

22899

diagram downward connector

Check minimum number of events None

22899

diagram downward connector

Include endpoints None

22899

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

22254

diagram downward connector
M13_ARTHTROSIS_COX

Control definitions

Control exclude M13_ARTHROPATHIES

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M15-M19
Name in latin Coxarthrosis

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 22254 11896 10358
Unadjusted prevalence (%) 5.90 5.64 6.23
Mean age at first event (years) 64.21 63.93 64.53

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.26 [1.00, 1.59] 4.8e-2 2853
15 years 0.01 0.95 [0.80, 1.12] 5.3e-1 1470
5 years 0.00 1.41 [1.23, 1.60] 3.2e-7 688
1 year 0.00 1.71 [1.41, 2.08] 7.6e-8 158

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: M13_ARTHTROSIS_COX – Coxarthrosis,
GWS hits: 51

Survival analyses between endpoints

↥

Plot

before Coxarthrosis,
after Coxarthrosis,

loading spinner Loading survival analyses plot