Urticaria

L12_URTICARIA

urticaria: A vascular reaction of the skin characterized by erythema and wheal formation due to localized increase of vascular permeability. The causative mechanism may be allergy, infection, or stress.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Remove individuals based on genotype QC

10175

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L12_URTICARIA

Control definitions

Control exclude L12_URTICARIAERYTHEMA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 10175 7303 2872
Unadjusted prevalence (%) 2.70 3.46 1.73
Mean age at first event (years) 41.36 40.89 42.57

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.63 [1.08, 2.43] 1.9e-2 474
15 years 0.01 1.10 [0.78, 1.56] 5.9e-1 200
5 years 0.00 2.29 [1.71, 3.05] 1.9e-8 117
1 year 0.00 4.69 [3.25, 6.78] 1.8e-16 44

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_URTICARIA – Urticaria
GWS hits: 4

Survival analyses between endpoints

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Plot

before Urticaria
after Urticaria

loading spinner Loading survival analyses plot