Urticaria

L12_URTICARIA

urticaria: A vascular reaction of the skin characterized by erythema and wheal formation due to localized increase of vascular permeability. The causative mechanism may be allergy, infection, or stress.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Remove individuals based on genotype QC

10175

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L12_URTICARIA

Control definitions

Control exclude L12_URTICARIAERYTHEMA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 10175 7303 2872
Unadjusted prevalence (%) 2.70 3.46 1.73
Mean age at first event (years) 41.36 40.89 42.57

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.63 [1.08, 2.43] 1.9e-2 474
15 years 0.01 1.10 [0.78, 1.56] 5.9e-1 200
5 years 0.00 2.29 [1.71, 3.05] 1.9e-8 117
1 year 0.00 4.69 [3.25, 6.78] 1.8e-16 44

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: L12_URTICARIA – Urticaria
GWS hits: 4

Survival analyses between endpoints

Plot

before Urticaria
after Urticaria

loading spinner Loading survival analyses plot